The history of Mecfond has its roots in 1857 with the birth of Guppy, a factory founded by an English engineer. Guppy specialized in the naval mechanics sector, also focusing on the formation of the urban fabric, which at the time saw Naples and the Kingdom of the Two Sicilies as an example to follow in terms of development and modernity. Guppy, in fact, also created the supports for the lamps of the first gas lighting in Naples and later, a locomotive capable of overcoming even hilly slopes.

In 1885-86 Guppy was converted into a joint stock company thanks to the intervention of an English company in the branch and became Società industriale napoletana Hawthorn-Guppy, which was dedicated to the construction of large engine systems for ships. Going through the period of Italian reunification, Hawthorn-Gruppy was involved in the Giolitti government's programs to re-transform the southern industrial fabric and was then taken over by the Milanese company Officine Meccaniche. With some interventions by the Giolitti government, the industrial fabric of Southern Italy was transformed and at the beginning of the 1860s, the original Guppy became Officine Meccaniche e Fonderie Napoletane.

From the merger between Officine Meccaniche e Fonderie Napoletane (which had taken the name MECFOND since '63) and FMI Fabbrica Macchine Industriali, FMI MECFOND S.p.A. (controlled by Finemccanica) was born. It is during these years that Mecfond's strong commitment to the Automotive sector developed. During those years Mecfond built and sold machines under license from the Danly Machine Corporation of Chicago. These were years of great commitment, in which Mecfond acquired orders from all the major car manufacturers, such as Volvo, Renault, Citroen, Fiat and Alfa Romeo. Mecfond was not exclusively synonymous with Automotive; in fact, there are numerous international testimonies of the contribution given by Mecfond in other sectors, such as food preservation. Around 1980, Finsider (IRI group) took over the company, transforming it into Nuova MECFOND S.p.A. Difficult years followed, during which the company changed owners again, also ending up in the orbit of the German Müller-Weingarten.

In 1999, the Neapolitan entrepreneur Giorgio Nugnes, previously an employee, started a dense investment program, thus the current MECFOND S.p.A. was born. Mecfond grew in terms of staff and turnover, regaining its role as a protagonist in the Italian and international market. The efforts are demonstrated by a continuous desire for research and improvements and the exploration of other markets, underlined by the collaboration on important projects in the Aerospace field.
To underline this commitment, there is the birth in 2007 of Mecfond Aerospace, already a leader in the manufacturing of parts and subassemblies in light alloy. Mecfond projects itself into the future, after having left an important historical mark, with the awareness of being a witness of the Southern industrial tradition and the desire to leave its mark also in the years to come.